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Geftinib Iressa 184475-35-2
Product Name: Gefitinib
Synonyms: Gefitinib N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;IRESSA;GEFITINIB;AKOS 91371;n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine;Gefitinib 184475-35-2;Gefitinib(TINIBS)
CAS No: 184475-35-2
Molecular Formula: C22H24ClFN4O3
Molecular Weight: 446.9
EC No: 643-034-7
Usage: Gefitinib, is a drug used for certain breast, lung , and other cancers, also known as Iressa, a selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, for the treatment of prior locally advanced or metastatic non-chemical treatment
or unsuitable for chemotherapysmall cell lung cancer (NSCLC).
Test items |
Specification |
Characters |
A white or almost white crystalline powder |
Appearance of solution |
Meets the requirements |
pH |
3.0-4.5 |
Specific optical rotation |
232º~239º |
Related substances |
Each of impurities A,B,C,D,E≤0.2% |
Any other impurity ≤0.1% |
|
Total impurities ≤0.3% |
|
Heavy metals |
≤0.002% |
Loss on drying |
≤0.5% |
Sulphated ash |
≤0.1%
|
Assay |
98.5%~101.0% |
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