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Keywords
425386-60-3 LY-450139 stem cell
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BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details:
Semagacestat is an inhibitor of the γ-secretase complex that blocks the production of Aβ38 (IC50 = 12.0 nM), Aβ40 (IC50 = 12.1 nM), and Aβ42 (IC50 = 10.9 nM) from H4 human glioma cells stably overexpressing human wild-type APP into the culture medium.
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