CasNo.761446-44-0,761446-44-0 factory price 1-METHYLPYRAZOLE-4-BORONIC ACID PINACOL ESTER,(761446-44-0) Suppliers

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761446-44-0 1-METHYLPYRAZOLE-4-BORONIC ACID PINACOL ESTER C10H17BN2O2

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2..Material Safety Data Sheet (MSDS)

3.Technical Data Sheet(TDS)

4.Route of synthesis (ROS)

5.Nuclear Magnetic Resonance(NMR)

6.Method of Analysis(MOA)

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1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Basic information

Product Name: 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Synonyms: 1-METHYL-4-1H-PYRAZOLEBORONIC ACID, PINACOL ESTER;1-METHYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-1H-PYRAZOLE;1-METHYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE;1-METHYL-1H-PYRAZOLE-4-BORONIC ACID PINACOL ESTER;1-METHYLPYRAZOLE-4-BORONIC ACID PINACOL ESTER;1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 97+%;1-Methyl-4-(4,4,5,5-Tetramethy;1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-

CAS: 761446-44-0

MF: C10H17BN2O2

MW: 208.07

EINECS:

Product Categories: Organoborons;Pyrazole;Boronic acid;Heterocyclic Building Blocks;Boronate Esters;Boronic Acids and Derivatives;Chemical Synthesis;Heteroaryl Boronate Esters;Organometallic Reagents

Mol File: 761446-44-0.mol

1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Chemical Properties

mp 59-64 °C(lit.)

storage temp. Refrigerator (+4°C)

CAS DataBase Reference 761446-44-0(CAS DataBase Reference)

Safety Information

Hazard Codes Xn,F,Xi

Risk Statements 22-36/37/38

Safety Statements 26-36-37/39

WGK Germany 3

Hazard Note Irritant/Flammable

HazardClass IRRITANT

MSDS Information

Provider Language

SigmaAldrich English

1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Usage And Synthesis

Chemical Properties White to light yellow crystal powde

Usage Reagent used for• ;Suzuki-Miyaura cross-coupling reactions1,2,3• ;Transesterification reactions4Reagent used for preparation of• ;Aminothiazoles as γ-secretase modulators5• ;Amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy6• ;Pyridine derivatives as TGF-β1 and activin A signalling inhibitors7• ;MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer8

Usage suzuki reaction

1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Preparation Products And Raw materials

Raw materials Tetrahydrofuran-->Potassium hydroxide -->n-Butyllithium-->Iodomethane-->Trimethyl borate-->Methyl bromide -->Pinacol-->MOLECULAR SIEVE-->4-Bromopyrazole