Human Bnp-32 Nesiritide Brain Natriuretic Peptide for Heart Failure

Details:

Nesiritide  (BNP-32), know as B-Type Natriuretic Peptide, BNP 32, Brain Natriuretic Peptide 32, Type-B Natriuretic Peptide, Ventricular Natriuretic Peptide, B type.

Product Description

Human BNP serves to compensate for deteriorating cardiac function causing preload and afterload reductions, natriuresis, diuresis, suppression of the renin-angiotensin-aldosterone system (RAAS) and endothelin-1, and lowering of norepinephrine. Based on its unique pharmacologic profile, nesiritide results in clinically significant balanced vasodilation of arteries and veins, and may be well suited for patients presenting with various scenarios of decompensated CHF usually due to volume overload (NYHA classes II-IV).
Unlike nitroglycerin, tachyphylaxis did not appear to occur with Natrecor. The complete efficacy profile of nesiritide included preload reduction (PCWP and RAP), reductions in pulmonary artery pressures, afterload reduction (systemic vascular resistance), and increases in cardiac index and stroke volume index (which are dose-dependent and not the result of a direct inotropic effect), without increasing heart rate.
Unlike inotropes, the beneficial hemodynamic effects produced by nesiritide do not cause an increase in myocardial oxygen consumption (MVO₂), an important consideration for patients with acutely decompensated heart failure. Because Nesiritide is not an inotrope, it does not affect myocardial contractility, as does a beta-adrenergic receptor agonist, or a phosphodiesterase III inhibitor. As a result, nesiritide is not arrhythmogenic.  

PRAMETERS
Name: Nesiritide  (BNP-32) 

Cas No: 124584-08-3

Formula: C143H244N50O42S4

Molecular:3464.04

Purity:98%

Appearance: white powder

Source: synthetic

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A: We are an GMP approved manufacturer specialized in peptides API products, OEM is available, Key products have obtained USDMF and EDMF. Production lines passed US and EU Authorities audit.

Q2. What is your MOQ

A: We support trial order, 1g is min. 

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A: Can be shipped within 2days after payment.

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A: Our products sold worldwide expecially to Europe, North America, South America and Africa.