- Min.Order :1 Gram
- Purity: ≥95%
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Keywords
1429882-07-4 4-[2-(2-cyclopropylethylamino)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexan-1-ol cas 1429882-07-4
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- Appearance:Crystalline Solid
- Application:research use
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BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
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MRX-2843 is a dual inhibitor of MerTK and FLT3 with IC50 values of 1.3 and 1 nM, respectively. It induces apoptosis and inhibits colony formation in AML cell lines and other tumor cells expressing MERTK and/or FLT3-ITD. Treatment with MRX-2843 significantly prolonged survival of AML mouse models.
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