Acetato de octreotida,octreotida,Octreotide Acétate d'octréotide,Октреотид,octréotide Acetato de octreotida,Октреотид ацетат
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What's Octreotide Acetate
Octreotide Acetate is the acetate salt of a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone.
Applications
NREMS and SWA were normal after 1 µgoctreotide. REMS, however, enhanced significantly during the light period. The increases in REMS started 2-3 h postinjection and persisted during the rest of the day, although they were very small when the individual hours were considered. In response to 10 µg octreotide, NREMS was significantly suppressed in hour 1 postinjection. Calculated for the 12-h light period, NREMS or SWA did not differ between the baseline and the octreotide days.
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