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80489-90-3 cas 80489-90-3 Amorfrutin 1
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BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
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Amorfrutin is a natural product isolated from A. fruticosa and G. foetida. Amorfrutin exhibits antidiabetic properties. Amorfrutin binds to and activate PPARγ with a Ki of 0.236 µM and activates a PPARγ gene reporter assay with an EC50 value of 0.458 µM, which results in selective gene expression involved with lipid and glucose metabolism. Amorfrutin is a glucose-lowering agent and can improves insulin sensitivity, glucose tolerance and blood lipid variables without increase of fat storage or hepatoxicity.
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