ONO-4819 cas 256382-08-8 Inhibitor
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Rivenprost is a potent and selective agonist for the EP4 receptor. It is selective for EP4 receptor over EP3, EP2, and EP1 receptors with Ki values of 0.7, 56, 620, and >10,000 nM for EP4, EP3, EP2, and EP1, respectively. It has been used to promote EP4-mediated bone formation, prevent bone loss related to osteoporosis, drive osteoblast differentiation, and stabilize bone implants.
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