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128446-35-5 Auxiliaries and Other Medicinal Chemicals Pharmaceuticals
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Product name
2-Hydroxypropyl-beta-cyclodextrin CAS:128446-35-5
Packaging, Storage &Shelf Life
Package
1kg/bag,25kg/ drum
Storage
Stored in original packaging for two years at a temperature not exceeding 40°C.
Shelf life
2 years if sealed and stored properly.
Specification
Item |
Index |
Appearance |
White crystalline powder, non-toxic, odorless, sweet |
Content |
≥98% |
Degree of substitution |
Confirm |
Water |
≤6.0% |
Residue on ignition |
≤1.5% |
Heavy metal |
≤0.0025% |
Arsenic |
≤0.0002% |
The total number of germ |
≤1000 |
The total number of mould |
≤100 |
Pathogenic bacteria |
≤none |
Function
Hydroxypropyl Beta cyclodextrin (HP – beta- CD) is beta Cyclodextrin a hydroxyl alkylation derivatives.Widely used in Pharmaceutical Drug for human,Food,Cosmetic and Chemical.
(1) In Medical Field
1.An ideal injection solubilizer and drug excipients because of lower surface activity and hemolytic activity, no muscle irritation.
2.Hydroxypropyl Beta Cyclodextrin can increase the solubility of the medicine and biological availability, also increase durg's curative effect thus decrease the dose.
3.Meanwhile,Hydroxypropyl Beta Cyclodextrin can control drug release rate, lower drug toxicity and enhance stability.
4. It is not only be used in oral drugs, injection, mucosal drug delivery system, transdermal drug delivery system, lipotropy targeting drug carrier, but also can be used as protein protective agent and stabilizer.
(2) In Food field
1.Hydroxypropyl Beta Cyclodextrin can prevent evaporation of volatile substances maintaining the stability of its nutrients, get rid of the terrible smell and can significantly enhance the effects of emulsification with the combined use of food emulsifiers.
2.Hydroxypropyl Beta Cyclodextrincan also make preservative of food release slowly, raise the effect of anti-corrosion and extend the shelf life of food.
3. In the food industry,because its molecule structure,HPBCD are employed for the preparation of cholesterolfree products.
(3)In Cosmetics Industry
1. Hydroxypropyl Beta Cyclodextrin is used as stabilizers, emulsifiers, deodorant in cosmetic.
2. Hydroxypropyl Beta Cyclodextrin can decrease the stimulating effect on the skin produced by organic composition of cosmetic.
3. Hydroxypropyl Beta Cyclodextrin can prevent nutrient ingredient evaporating and oxidating, increase water-soluble of spices and essence, keep fragrance's sustained and release lasting.
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