917562-33-5 cas 917562-33-5 2-Chloro-N-[4-(4-methoxyphenyl)-2-thiazolyl]-N-(3-methoxypropyl)acetamide
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JT010 is a TRPA1 channel activator (EC50 = 0.65 nM) with potent selectivity for TRPA1 over TRPV1, TRPV3, TRPV4, TRPM2, TRPM8, and TRPC5 channels (EC50 values are >1 μM). It activates the TRPA1 channel by covalently and site-selectively binding to Cys621.
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