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97792-45-5 Herbal Extract pharmaceutical raw material
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Product name: LAPPACONITINE HYDROBROMIDE
Cas:97792-45-5
Function:
1. Analgesic effect: Intraperitoneal injection of homogenin hydrobromide can obviously alleviate the thermal pain of chronic constrictive injury (CCL) rats, achieve analgesic treatment effect, and there is no obvious toxicity.
2. Anti-inflammatory effect: Uracidin has a significant inhibitory effect on the swelling of mouse ear shells caused by xylene, swelling of arthritic feet in rats, and agar granuloma hyperplasia in rats.
It shows that coltanin has anti-acute and chronic inflammatory effects, which provides a theoretical basis for the clinical use of coltanin in the clinical treatment of pain and redness caused by rheumatism and rheumatoid arthritis.
3. Antitumor effect: The inhibitory rate of scopolamine on mouse liver cancer was 11.20% -53.08%, and the inhibitory rate on mouse S180 was 29.81% -53.%. This shows that aconitin hydroaluate has a certain effect on anti-mouse liver cancer S180, and has no significant effect on the body weight of mice.
4, anti-arrhythmic effect: high aconitine can increase the normal threshold of arrhythmia induced by aconitine in rats, and can significantly improve myocardial ischemic arrhythmia in dogs, thereby reducing the incidence of arrhythmia, and its mechanism of action may be It blocks sodium channels.
Specification:
MF: | C32H45BrN2O8 |
MW: | 665.61 |
Product Categories: | Miscellaneous Natural Products;Inhibitors;Pyridines |
Mol File: |
97792-45-5.mol |
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