LDN-214117/ supplie...

LDN-214117/ supplier with competitive price in stock-Rechems

LDN-214117/ supplier with competitive price in stock-Rechems

Min.Order / FOB Price:Get Latest Price

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Negotiable

  • Min.Order :0
  • Purity: 98%

Keywords

LDN-214117 LDN214117 1627503-67-6 manufacturer

Quick Details

  • Appearance:
  • Application:Medicinal Chemistry 、 Biomedicine、 Pharmaceutical intermediate、 Chemistry experiment 、Biological experiments 、Chemical reagent、 For R&D use only.
  • PackAge:Bottle and bag according to customer
  • ProductionCapacity:
  • Storage:Stored in well-closed containers
  • Transportation:DHL,UPS,FEDEX EMS or as your request

Superiority:

1.Custom synthetic service could be provided and COA/HPLC/HNMR is available.
2.Professional synthesis laboratory and production base.
3.Strong synthesis team and service team.
4.Professional data management system.
5.We provide the professional test date and product information.
6.Rich shipping methods,ex. Fedex,DHL,TNT,BY SEA and BY AIR.
7. We can accept various payment methods,Paypal,T/T, etc.
8.Professional packaging can be according the customers’requirment.

Details:

LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM; > 100 fold selectivity for ALK5; also inhibits BMP6(IC50=100 nM).IC50 value: 22 nM(ALK2) Target: ALK2 inhibitor LDN-214117 is a highly BMP selective compound, significantly biased toward ALK2 and its cognate ligands including BMP6 and also demonstrates a high degree of kinome selectivity and low cytotoxicity.LDN-214117 may be useful as highly selective probes of BMP-mediated cellular physiology that may provide a useful complement to the dorsomorphin class of compounds.Furthermore, this class of BMP inhibitors offers a structurally distinct template for the development of therapeutics for the treatment of BMP signaling-mediated diseases such as FOP.
Shanghai Rechem science Co., Ltd.
Rechemsis focus on R&D of new APIS, signal transduction inhibitors and pharmaceutical intermediates. We follow closely the industry trend, and the latest research achievements in life science area.
Rechems is located in the largest biomedical base in China--Shanghai and cooperatively established modern production base and laboratory in surrounding areas. We have built up a good relationship with many US / European / Japanese pharmaceutical companies to conduct chemical research and inventory trading in medicinal chemistry.
Rechems's mission is to serve pharmaceutical community by providing excellent services and high-quality products in a timely manner.
Rechems's vision is to be recognized by our clients as one of the best suppliers of chemical products for our superior quality, efficient and cost-effective services.
We insist the principle of "Quality first, customer foremost, best credit, be pioneering and creative", looking forward to establishing good business relationships with customers all over the world. Let's work together for bright future!

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