carbopol 940

Superiority:

Pinyin name: Kabomu

English name: Carbomer

Product name: carbopol, divided into 934, 940, 941 and so on according to viscosity

Page number: 2005 edition part ii -897

Carbomer formula C3H4O2

[properties] this product is white loose powder;Characteristic slight odor;It has the ability to induce moisture.

[identification] take 0.1g of this product, disperse it in 20ml water, add 0.4ml of 10% sodium hydroxide solution, and it will be gelatinous.

Acidity, 0.10 g, proper check 】 【 evenly dispersed swelling in 10 ml water, check (appendix Ⅵ H) in accordance with the law, the pH value should be 2.5 ~ 3.5.

Benzene take this product about 1g, precision weighing, add paraxylene into each 1ml containing 10 g solution, as a control solution;Take another about 1g of this product,

Precise weighing was performed. In the test tube with plug, 10.0ml of p-xylene was added to disperse the product by vibration, and 10.0ml of 0.1mol/L sodium hydroxide solution was added to vibrate the dense plug

Shake for 1 hour and take the supernatant as the test solution.Precision measuring reference substance solution with each 1 mu l solution, according to gas chromatography (appendix Ⅴ E)

A 3m glass chromatographic column was used. The supporting body was 201 red (60 ~ 80 mesh). The solid was mixed equally with dinonyl phthalate and organic bentonite

Fixed liquid, coating concentration is 10%, in the column temperature 100℃ determination.Benzene content should not exceed 0.01%.

Dry weight loss take this product, 1 hour at 80 ℃ decompression drying, loss of weight reduction shall not be over 2.0% (appendix Ⅷ L).

On ignition residue, 1.0 g, proper inspection (appendix Ⅷ N) in accordance with the law and legacy residue may not be over 2.0%.

Take on ignition of heavy metal residue under a legacy of the residue, check the second method (appendix Ⅷ H) in accordance with the law, containing heavy metals shall not be twenty over one million.

The viscosity is 0.5g, evenly dispersed in 98ml water. After full swelling, mix well, and adjust the pH value with 15% sodium hydroxide solution to

7.3 ~ 7.8 (with precision pH test paper test), add water to 100 ml, blending, avoid to produce bubbles), in accordance with the determination of the second method (appendix Ⅵ G), at 25 ℃

When the dynamic viscosity should be 15 ~ 30Pa·S.

【 content determination 】 this product is about 0.4 g, precision said, evenly dispersed in 400 ml water, stir to dissolve, as potential titration method (appendix Ⅶ

A) per 1ml of sodium hydroxide titrant

(0.25mol/L) is equal to 11.25mg of -- COOH.

[category] pharmaceutical excipients.

Store under seal.

【 data 】 cosmetics commonly used thickener - kapo