(S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide Chemical Properties
Boiling point 632.3±55.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
pka 12.13±0.29(Predicted)
Safety Information
MSDS Information
(S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide Usage And Synthesis
Application Ostarine is a non-steroidal agent with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, thus promoting and/or maintaining libido, fertility, prostate growth, and muscle growth and strength. Mimicking testosterone's action, this agent may increase lean body mass, thereby ameliorating muscle wasting in the hypermetabolic state of cancer cachexia.
Ostarine has been used in trials studying the treatment of Stress Urinary Incontinence and Triple Negative Breast Cancer.
Physiological action Ostarine is a selective androgen receptor modulator (SARM) with Ki of 3.8 nM. Plasma concentration of ostarine declines in a biexponential manner after intravenous administration with terminal half-live of 6.0 hours. In vivo, ostarine significantly stimulates the growth of prostate, seminal vesicles, and levator ani muscle in castrated rats. Ostarine restores the weights of the prostate to 39.2%, of that observed in the intact control. The weight of seminal vesicle is also restored by ostarine to 78.8%, respectively, of that observed in the intact control. Ostarine stimulates the growth of levator ani muscle to a greater extent than androgenic organs, to 141.9%.
Uses Ostarine is nonsteroidal selective androgen receptor modulator (SARM) used in the treatment of osteoporosis and muscle wasting in animal models. A potential compound for the treatment of hypoactive sexual desire disorder.