leuprolide 74381-53...

leuprolide 74381-53-6
leuprolide 74381-53-6
leuprolide 74381-53-6

leuprolide 74381-53-6

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10 Kilogram

Negotiable

  • Min.Order :10 Kilogram
  • Purity: 98%
  • Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram,Other

Keywords

leuprolide 74381-53-6 manufacturer , better price with good quality

Quick Details

  • Appearance:Fluffy Solid
  • Application:Organic Chemistry
  • PackAge:Depended
  • ProductionCapacity:300|Kilogram|Month
  • Storage:KEEP COLD
  • Transportation:BY SEA OR AIR

Superiority:

Leuprorelin acetate Basic information
Anti-cancer drugs
Product Name: Leuprorelin acetate
Synonyms: leutenizinghormone-releasingfactor(pig),6-d-leucine-9-(n-ethyl-l-prolinamid;lupron;tap-144;tap-144-sr;DES-GLY10,[P-LEU6]-LH-RH ETHYLAMIDE;[DES-GLY10, D-LEU6, PRO-NHET9]-LH-RH (HUMAN);(DES-GLY10,D-LEU6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING FACTOR;(DES-GLY10,D-LEU6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING HORMONE
CAS: 74381-53-6
MF: C59H84N16O12.C2H4O2
MW: 1269.46
EINECS:  
Product Categories: Organics;Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Gonadotropin-releasing hormone (GnRH);Anti-cancer&immunity
Mol File: 74381-53-6.mol
Leuprorelin acetate Structure
 
Leuprorelin acetate Chemical Properties
mp  150-155°C
storage temp.  −20°C
 
Safety Information
Safety Statements  22-24/25
WGK Germany  2
RTECS  OH6390000
MSDS Information
Provider Language
SigmaAldrich English
 
Leuprorelin acetate Usage And Synthesis
Anti-cancer drugs Leuprolide acetate is a commonly used hormone anti-cancer drug, , it is a acetate of leuprolide which is a nonapeptide synthetic analogue of LHRH( one kind decapeptide), it is a LH-RH antagonist, LHRH is produced by the hypothalamus, it can promote pituitary for the release of gonadotropins and follicle-stimulating hormone (FSH) and luteinizing hormone (LH). This product’s structure is similar to LHRH, its acting on the anterior pituitary which prompts FSH, LH release function, increases serum concentrations of testosterone and dihydro testosterone. It is used as maintenance therapy for advanced prostate cancer clinically, but in about one week after use of the product, the number of active receptors will be reduced, and gonadotropin secretion will be reduced.After 2 to 4 weeks, the concentration of testosterone and dihydro testosterone can be reduced to castration levels. After the withdrawal, gonadotropin and androgen concentrations can be recovered to normal. 
Note that this product is not effective when administered orally, subcutaneous or intramuscular administration has good absorption. T1 / 2 of parenteral administration is 3 h. There is no accumulation in the body, unchanged drugs and its metabolites in urine excretion rates are2.9% and 1.5%, respectively. Ethanol can enhance the role of this product, the course of treatment should not drink, in case it is difficult to control the incidence of adverse reactions. In the first week of the course of treatment ,patients should try to be hospitalized for monitoring, choose an experienced physician to guide treatment to prevent severe neurological complications, urinary tract obstruction. Injection site should often vary. 
The above information is edited by the chemicalbook of Tian Ye.
Chemical Properties Fluffy Solid
Usage Synthetic nonapeptide agonist analog of LH-RH. Antineoplastic (hormonal).
 
Leuprorelin acetate Preparation Products And Raw materials
 

 

Details:

Henan Sunlake Enterprise Corporation is located in Henan Province, the central plain of China , Which enjoys favorable geogeaphical position and convenient transportion. The comany was established in june 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
     Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs ,  Water treatment chemicals , Food & FEED additives and others . These products have been being well exported to Europe , Southeast Asia , the Middle East ,  Africa , South America and some other countries and areas.
    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team who are professional engineers and scholars with Ph. D. .So we are confident to serve you  better with our high - quality products and professional team.
    We are taking great efforts to provide our customers with demanded goods and professional services, continuously improve our core ability of competition and get the momentum for sustainable development ,Which finally makes us being a reliable and professional supplier in international market.
     We welcome any inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!
 
Our Advantages:
I). We have abundant professional production experience.
II). We have our own chemical factory.
III). Sample is free of charge.
IV). Reasonable Price, Excellent Quality & Attentive Service
V). Prompt reply: we can reply your inquiry and email within 24 hours.
VI). Fast Delivery: The delivery time is about 10-20 days after receiving the deposit.
VII). We have passed the LFGB, SGS, STC, HSL and some other tests.
VIII). We have a unity cooperation team.

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