Tenofovir Disoproxi...

Tenofovir Disoproxil Fumarate 202138-50-9

Tenofovir Disoproxil Fumarate 202138-50-9

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1 Kilogram

FOB Price: USD 10.0000

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,

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202138-50-9 Tenofovir Disoproxil Fumarate Tenofovir Disoproxil Fumarate supplier

Quick Details

  • Appearance:White powder
  • Application:Local anesthetic; Pharmaceutical intermediate; Research chemical
  • PackAge:25KG/DRUM
  • ProductionCapacity:10000|Kilogram|Month
  • Storage:2-8°C
  • Transportation:By air, by sea, by express delivery

Superiority:

Hanways focus on:

-Pharmaceutical raw materials

-Chemical raw materials

-Food additives

-Flavors and fragrances

-Feed additives

-Plant extracts

-Veterinary raw materials

 

We could supply you:

-Best quality

-Competitive price

-Perfect services

Pls contact with us freely for getting detailed product specifications, product tech. date sheet, COA and MSDS.

Pls contact with us freely for getting prices, delivery time and payment terms.

Details:

Company Profile:

Year Established: 2009

Major export product: Tacrolimus, UDCA, Fluorometholone, Mifepristone, Finasteride, Fulvestrant

Major application: Pharmaceutical and Chemical raw materials

 

Product Name:Tenofovir Disoproxil Fumarate
CAS:202138-50-9
MF:C23H34N5O14P
MW:635.51
EINECS:1308068-626-2
Product Categories:Inhibitors;Tenofovir;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Phosphorylating and Phosphitylating Agents
Mol File: 202138-50-9.mol
 
Tenofovir disoproxil fumarate Descriptions
 
Tenofovir is used in combination with other medicines for the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immunodeficiency syndrome (AIDS).
 
Tenofovir disoproxil fumarate Pharmacokinetics
 
Tenofovir is hardly absorbed through the gastrointestinal tract, for this reason, prodrug of Tenofovir has been developed by esterification, and then to make tenofovir fumarate ester. Tenofovir ester is water-soluble, can be rapidly absorbed and degraded into the active tenofovir, and then was metabolized to the active Tenofovir disoproxil .
 
Tenofovir will reach the peak of plasma Concentration within 1-2 h after administration. When combined with food service, the bioavailability of Tenofovir can be increased by 40%. Intracellular half-life of Tenofovir disoproxil is about 10 h, it needs dosing everyday. Because Tenofovir is not a CYP-450 substrate, this may decrease the possibility of interactions with other drugs caused by CYP450. Elimination of Tenofovir is by glomerular filtration and active tubular secretion. Approximately 70% to 80% is recovered in urine as unchanged drug. Elimination half-life is approximately 17 h .
 
Indications: Tenofovir is indicated for the treatment of HIV, HBV infection. This product also can cooperated with other reverse transcriptase inhibitors for HIV-1 infection and hepatitis B treatment .
 

Packing:

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Province and cooperative factories in Zhejiang Province.

 

The leading products range of the company is antineoplastic, cardiovascular and antibiotics. With our strong technical force, under the sustained effort of the whole staff, we have built high efficient and swift sales system. The company’s sales network covers more than twenties countries and areas, also we built good and long relations with many big pharmaceutical company worldwide.

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