Buy High quality ≥95% 65928-58-7 Dienogestrel
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65928-58-7 Dienogestrel Buy 65928-58-7 High quality ≥95% 65928-58-7
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Dienogest is a progestin, or a synthetic progestogen, of the 19-nortestosterone group. It is available in combination with estradiol valerate or ethinylestradiol for use as an oral contraceptive, and by itself for the treatment of endometriosis in Europe, Australia, and Japan. Although available in combination with estrogen as a contraceptive in the United States, dienogest is not available in this country by itself. In addition to its progestogenic effects, dienogest has antiandrogenic activity, and as a result can improve androgenic symptoms such as acne. It is a non-ethynylated progestin which is structurally related to testosterone.
Dienogest, a synthetic nortestosterone derivative, is a selective progesterone receptor agonist. Although dinogest binds to the progesterone receptor of the human uterus with only 10% of the relative affinity of progesterone, it has a strong progestogenic effect in vivo. In addition, dienogest displays moderate anti-gonadotrophic effects, but no androgenic, glucocorticoid or mineralocorticoid activity in vivo. It is reported that the agonist activity is approximately one third of that of cyproterone acetate. Dienogest has been used in the treatment of endometriosis by reducing the endogenous production of estradiol
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Dienogest is an orally active synthetic progesterone (or progestin). It is available for use as an oral contraceptive in combination with ethinylestradiol. It has antiandrogenic activity and as a result can improve androgenic symptoms. It is a non-ethinyl
| Catalogue Number | D441870 |
| Chemical Name | Dienogest |
| Synonyms | (17α)-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile; 17α-Cyanomethyl-17β-hydroxyestra-4, 9-dien-3-one; Dienogestril; Endometrion; STS 557; |
| CAS Number | 65928-58-7 |
| Molecular Formula | C??H??NO? |
| Appearance | Off-White to Pale Yellow Solid |
| Melting Point | 210-2140C |
| Molecular Weight | 311.42 |
| Storage | -20°C Freezer |
| Solubility | Chloroform (Slightly, Heated), Pyridine (Slightly) |
| Category | Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Derivative of 19-Nortestosterone. In combination with estrogen as oral contraceptive. Progestogen. |
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