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Best price 4093-35-0 in stock Bromopride manufacturer

Best price 4093-35-0 in stock Bromopride manufacturer

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Best price 4093-35-0 Bromopride 4093-35-0 in stock Bromopride manufacturer

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Bromopride is a dopamine D2 receptor antagonist (Ki = 14 nM).It binds to bovine anterior pituitary membranes with an IC50 value of 2.13 μM. Bromopride inhibits cholinesterase activity in vitro in rat plasma and striatum homogenate (IC50s = 67.8 and 38.4 μM, respectively). It increases serum prolactin levels in rats by 100% when used at a dose of 0.02 mol/kg. Bromopride (2.5 mg/kg) decreases locomotion and rearing in an open field test and impairs acquistion, but not retention, of a conditioned avoidance response in a two-way active conditioned avoidance test in rats.

Bromopride (free base) is a dopamine antagonist with prokinetic properties widely used as an antiemetic

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Bromopride is a dopamine antagonist used as an antiemetic. Its prokinetic properties are similar to those of metoclopramide. It is unavailable in America or the United Kingdom.

Bromopride is a dopamine antagonist with prokinetic properties, widely used as an antiemetic.

 

Catalogue Number B686645
Chemical Name Bromopride
Synonyms 4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide; 2-Methoxy-4-amino-5-bromo-N,N-diethylaminoethylbenzamide; N-Diethylaminoethyl-2-methoxy-4-amino-5-bromobenzamide; Emepride; Emoril; Viadil
CAS Number 4093-35-0
Molecular Formula C??H??BrN?O?
Appearance White to Off-White Solid
Melting Point 148 - 150°C
Molecular Weight 344.25
Storage Refrigerator
Solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications An antiemetic. Bromopride is used in method and a system for analyzing neuropharmacology of a drug.

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