Offer28416-82-2 exporterCompetitive price Fluticasone Intermediate

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Offer 28416-82-2 28416-82-2 exporter Competitive price Fluticasone Intermediate

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Fluticasone 17β-carboxylic acid is an intermediate in the synthesis of the glucocorticosteroid fluticasone propionate

Flumethason is a glucocorticoid receptor agonist. This complex binds to the nucleus causing a variety of genetic activation and repressions. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes.

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Catalogue Number	F599490
Chemical Name	Fluticasone 17β-Carboxylic Acid
Synonyms	(6α,11β,16α,17α)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxo-androsta-1,4-diene-17-carboxylic Acid; 6α,9α-Difluoro-11β,17α-dihydroxy-16α-methylpregna-3-oxo-1,4-diene-17β-carboxylic Acid;
CAS Number	28416-82-2
Molecular Formula	C??H??F?O?
Appearance	White to Off-White Solid
Melting Point	>290ºC (dec.)
Molecular Weight	396.42
Storage	Refrigerator
Solubility	Acetone (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
Category	Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	The major metabolite of Fluticasone. Anti-inflammatory agent.

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