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Altrenogest is a synthetic trienic C21 steroidal progestomimetic, belonging to the 19-nor-testosterone series. It is an orally active (pro)gestagen. Altrenogest acts by its liposolubility by penetrating the target cells where it binds to specific receptors.
Altrenogest is used to suppress estrus in mares in order to facilitate induction of normal estrous cycle activity. It is also used in mares to synchronize scheduled breeding activity. In the suppression of estrous behavior in mares, this is usually related to mares that are used as performance horses.
Altrenogest, sold under the brand names Swinemate and Altren manufactured by Aurora Pharmaceutical and Regumate manufactured by Merck, is a progestin of the 19-nortestosterone group which is widely used in veterinary medicine to suppress or synchronize estrus in horses and pigs. It is available for veterinary use in both Europe (as Regumate) and the United States (as Matrix).
Altrenogest is used for suppression of estrus. The mare will experience a predictable occurrence of estrus following drug withdrawal. This allows a regular cycle during the transition from winter anestrus to the physiological breeding season in mares with active ovaries. By managing the reproductive cycle, horse owners have more control over breeding procedures and the timing of the arrival of foals.
Product Number | A2892 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C21H26O2 = 310.44 |
Physical State (20 deg.C) | Solid |
Storage Temperature | 0-10°C |
Condition to Avoid | Heat Sensitive |
CAS RN | 850-52-2 |
Reaxys Registry Number | 7354843 |
PubChem Substance ID | 354333332 |
Merck Index (14) | 319 |
MDL Number |
MFCD00867855 |
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