Cyclosporin A cas 59865-13-3 KS-1257
Chemistry
Molecular Structure:
Molecular Formula: C62H111N11O12
Molecular Weight: 1202.6112
Classification Code: Anti-Infective Agents ; Antifungal agents ; Antirheumatic agents ; Dermatologic agents ; Drug / Therapeutic Agent ; Enzyme inhibitors ; Human Data ; Immunologic Factors ; Immunosuppressant ; Immunosuppressive agents ; Mutation data ; Reproductive Effect ; Tumor data
Melting point: 148-151°C
Index of Refraction: 1.467
Molar Refractivity: 328.83 cm3
Molar Volume: 1183.6 cm3
Surface Tension: 31.6 dyne/cm
Density: 1.016 g/cm3
Flash Point: 736.3 °C
Enthalpy of Vaporization: 218.52 kJ/mol
Boiling Point: 1293.8 °C at 760 mmHg
Uses
Cyclosporine (CAS NO.59865-13-3) is an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system and, so, the risk of organ rejection. It has been studied in transplants of skin, heart, kidney, liver, lung, pancreas, bone marrow, and small intestine.
Production
Cyclosporine (CAS NO.59865-13-3) is synthesized by a nonribosomal peptide synthetase, cyclosporine synthetase. The enzyme contains an adenylation domain, a thiolation domain, a condensation domain, and an N-methyltransferase domain.
Jinlan Pharm-Drugs Technology Co., Limited(with its export company Hangzhou Royall Import & Export Co.,Ltd.) is mainly engaged in R&D, manufacturing and marketing pharmaceuticals, chemical intermediates, Biochemicals, Veterinary medicines and Nutrition products. |
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