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(-)-Epigallocatechin gallate 989-51-5 anti-tumor effect
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Product Name:(-)-Epigallocatechin Gallate(EGCG)
Botanical Name: Camellia sinensis (L.)O.Ktze
Part of Used: green tea leaf
Specification: 90%,95%,98% by HPLC
Appearance: white fine powder
Water soluble: good water soluble
CAS No.:989-51-5
Mol. Formula: C22H18O11
Mol. Weight: 458.38
Epigallocatechin gallate (EGCG), the major catechin accounting for 59% of the total catechins in green tea, is a powerful antioxidant as well as an antiangiogenic and antitumor agent. EGCG has been studied for its role in the chemoprevention of a wild range of cancers, including liver, stomach, skin, lung, mammary gland and colon cancers. Study results show that EGCG is able to induce apoptosis, promote cell growth arrest and block carcinogenesis by affecting signal transduction pathways. Moreover, EGCG exhibits inhibition against a variety of viruses, including HCV, HIV-1, HBV, HSV-1, HSV-2, EBV, adenovirus, influenza virus and enterovirus, as well as several enzymes, including DNMTs, proteases and DHFR.
(1). anti-oxidation and anti-aging, eliminating free radicals;
(2). anti-cancer, inhibiting the increasing of cancer cell;
(3). anti-bacterium, with the function of sterilization and deodorization;
(4). With good inhibitory effect to HIV.
(1).Applied in food field, adds tea polyphenols in foods can maintain original flavor, preventing corruption and discoloration, with the function of restraining and killing bacteria, which will improve the food hygiene standards;
(2).Applied in pharmaceutical field, it is also used to treat cardiovascular disease and cancer;
(3).Applied in cosmetic field, protecting skin from the harmful sun exposure, which will prevent skin cancer.
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