99% Raw materials Nitrofurantoin Powder

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price:USD 60.0000 -75.0000

1 Kilogram

FOB Price:USD 60.0000 -75.0000

Min.Order :1 Kilogram
Purity: 99.5%min
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

High quality Nitrofurantoin Raw Material Nitrofurantoin Nitrofurantoin

Quick Details

Appearance:Yellow crystalline Powder
Application: The broad mechanism of action for this drug likely is responsible for the low development of resistance to its effects, as the drug affects many different processes important to the bacterial cell.
PackAge:AS YOUR NEED
ProductionCapacity:100|Kilogram|Day
Storage: Cool and Dry
Transportation:by sea or air

Superiority:

If there is a new supplier, our audit process will be as follows:

Supplier is GMP approved manufacturer and product is listed in GMP certificate

① GMP certificate validation from SFDA website

② At least 2 different batch sample test before contract

③ Only both approved，we wil buy

Supplier is non-GMP approved manufacturer or not GMP product

① Pre-shipment batch sample is a must

② If sample approved,we will visit manufacturer for auditing

③ At least 3 regular cooperating buyers comments

④ Only the above all approved，we will buy

We will provide you the sincerest and most professional services as follows:

Sales:

24hours to reply your E-mail

Market information trend share with customers

Suggestion for purchase decision

Financial:

Different payment terms: TT, LC, DP and so on

Sino-Sure credit application and market risk control

Shipment conditions:

Update the whole process from China to destination

10 days by air & 14 days by sea to finish usually

Fast custom clearance at destination

Doc after shipment date:

Same day for air shipment and LCL sea shipment

3 working days for FCL sea shipment

100% clear and perfect docs

Reputation:

Implementing contract terms strictly

Timely solve any discrepancy or goods claims

Take our responsibility for loss if it is our liability

Others:

Assistant: sample working; help you solve the problem in China with others

Registration: professional team for registration in market

Technology: rich experienced producing expert to support

Product Standard：BP/USP/EP

Documents：GMP/DMF/MSDC/CEP

About Arshine

Arshine Group, set up in Shenzhen in 2007, is one of the leading Health Medicine Raw Materials and Food Raw Materials exporters in China. Arshine Group has obtained international ISO9001 certification and FAMI-QS certification. In addition, We are AA customer of Sinosure and are authorized with customs AEO advanced certification.

Arshine Group is composed of 5 subsidiaries, including Arshine Pharmaceutical Co.,Ltd, Arshine Food Additive Co., Ltd, Arshine Animal Healthcare Co., Ltd, Arshine Life Science Co., Ltd and Hangzhou Arshine Branch. Arshine specializes in exporting human and veterinary API, vitamins, amino acids, minerals, food and feed additives and plant extracts etc. Arshine has exported around 2000 products to 90 countries and areas in Europe, Middle East, East Asia and South Asia. Since establishment, Arshine’s annual sales volume has increased from USD 1 million to USD 100 million, growing hundredfold in 10 years. Having established long-term cooperation with more than 800 manufacturers, Arshine is regional sales representative or even exclusive agent for many manufacturers nowadays. To our pride, Arshine ranks among top 10 in all pharmaceutical raw materials export enterprises in China, top 3 in the private exporters.

Details:

Nitrofurantoin, sold under the trade name Macrobid among others, is an antibiotic used to treat bladder infections.It is not effective for kidney infections. It is taken by mouth. Common side effects include nausea, loss of appetite, diarrhea, and headaches. Rarely numbness, lung problems, or liver problems may occur. It should not be used in people with kidney problems.While it looks like it is generally safe during pregnancy it should not be used near delivery.It works by slowing growth rather than killing bacteria.

Function

						The mechanism of action of nitrofurantoin is unique and complex. The drug works by damaging bacterial DNA, since its reduced form is highly reactive.This is made possible by the rapid reduction of nitrofurantoin inside the bacterial cell by flavoproteins (nitrofuran reductase) to multiple reactive intermediates that attack ribosomal proteins, DNA,respiration, pyruvate metabolism and other macromolecules within the cell. Nitrofurantoin exerts greater effects on bacterial cells than mammalian cells because bacterial cells activate the drug more rapidly. It is not known which of the actions of nitrofurantoin is primarily responsible for its bactericidal activity. The broad mechanism of action for this drug likely is responsible for the low development of resistance to its effects, as the drug affects many different processes important to the bacterial cell.

						Application 

						Nitrofurantoin has been available for the treatment of urinary tract infections (UTIs) since 1953. Its current uses include the treatment of uncomplicated UTIs and prophylaxis against UTIs in people prone to recurrent UTIs. Increasing bacterial antibiotic resistance to other commonly used agents, such as fluoroquinolones and trimethoprim/sulfamethoxazole, has led to increased interest in using nitrofurantoin.Several trials comparing nitrofurantoin to other commonly used agents have shown this drug results in similar cure rates for uncomplicated UTIs.The efficacy of nitrofurantoin in treating UTIs combined with a low rate of bacterial resistance to this agent makes it one of the first-line agents for treating uncomplicated UTIs as recommended by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases.Nitrofurantoin is not recommended for the treatment ofpyelonephritis,prostatitis and intra-abdominal abscess,because of extremely poor tissue penetration and low blood levels. It is used in the treatment of infections caused by these organisms.