54965-21-8 supplier Albendazole in bulk supply

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Albendazole is studied and developed by the company SmithKline Beecham (GSK's predecessor). It is a kind of broad spectrum thiabendazole class anthelmintics which can be applied by both human and animal. It can inhibit the parasite growth and reproduction by inhibiting the intestinal and absorbing the intracellular protein, resulting in the failure of parasite in sugar uptake which is indispensable for their survival, thus causing the endogenous glycogen depletion of insects and further inhibiting fumarate reductase system, preventing the generation of adenosine triphosphate, causing that the parasites are not be able to further survive and reproduce, and ultimately die due to energy depletion. Albendazole has capability of completely killing the eggs of whipworm and hookworm as well as partially killing Ascaris’ eggs; it can also get rid of various kinds of nematodes parasitizing inside animal bodies, and has effects on either getting rid of or directly killing tapeworms and cysticerci. It is thus useful in the treatment of hydatid and the nervous system (cysticercosis) caused by infection of pork worm, and also in the treatment of hookworm, roundworm, pinworm, nematode trichinella, tapeworm, whipworm and stercoralis nematode.

Albendazole is a broad-spectrum, synthetic benzimidazole-derivative anthelmintic. It interferes with the reproduction and survival of helminths by inhibiting the formation of microtubules from tubulin. This leads to an impaired uptake of glucose, a depletion of glycogen stores, and results in the worm's death.