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73231-34-2 Florfenicol Florfenicol 73231-34-2 bulk Florfenicol 73231-34-2
Florfenicol is a broad-spectrum fluorinated antibiotic and a derivative of thiamphenicol It is active against human clinical isolates of enteric bacteria, including E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, and Salmonella (MIC50s = 6.3-12.5 µg/ml). Florfenicol is also active against clinical isolates of various bovine and porcine respiratory tract pathogens, including P. multocida, A. pleuropneumoniae, and B. bronchiseptica (MIC50s = 0.25-4 µg/ml). It inhibits peptidyl transferase activity in 70S ribosomes isolated from E. coli when used at a concentration of 1 mM. Formulations containing florfenicol have been used in the treatment of infectious respiratory disease in cattle.
Florfenicol is a fluorinated synthetic analog of thiamphenicol (sc-213029) and broad spectrum antibiotic.
It is a kind of antibacterial drug. It is used as the veterinary antimicrobial drugs for treating bacterial diseases of pigs, chickens and fish. It has good efficacy in treating the infection disease of pigs, chickens and fish induced by sensitive bacteria, especially for treating respiratory infections and intestinal infections.
Catalogue Number | F405750 |
Chemical Name | Florfenicol |
Synonyms | 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide; (-)-Florfenicol; Aquafen; Aquaflor; Florfenicol; Nuflor; Sch 25298; |
CAS Number | 73231-34-2 |
Molecular Formula | C??H??Cl?FNO?S |
Appearance | White to Off-White Solid |
Melting Point | 152-154°C |
Molecular Weight | 358.21 |
Storage | -20°C Freezer |
Solubility | DMF (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
Category | Standards; Ephedrine; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines; |
Boiling Point | N/A |
Applications | Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial. |
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