Factory Supply Terbinafine Hydrochloride API Raw Powder CAS 78628-80-5 Terbinafine HCL

Factory Supply Terbinafine Hydrochloride API Raw Powder CAS 78628-80-5 Terbinafine HCL

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price:USD 10.0000 -20.0000

1 Kilogram

FOB Price:USD 10.0000 -20.0000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : L/C,T/T,

Keywords

Terbinafine Hydrochloride 78628-80-5 Terbinafine HCL

Quick Details

Appearance:White powder
Application:78628-80-5
PackAge:carton box
ProductionCapacity:1000000|Kilogram|Month
Storage:cool and dry
Transportation:by air by sea or by express

Superiority:

Product quality:

Our company have high quality product , and also the product we have good manufacture .

First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried out for one month.Besides，this type has a good viscosity. the prouct can make Gel hand sanitizer thickener cosmetics industry.

We can ensure the product quality , If the product is not satisfactory, you can return it at any time.

Manufacturing technique

In the chemical industry, the process of producing a chemical product. Including raw material pretreatment, reactant chemical reaction and chemical product separation purification, final packaging sales.

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Details:

Product information

Product Name: Terbinafine Hydrochloride
Purity: 98%min
Appearance: White crystalline powder
CAS No.: 78628-80-5
EINECS: 245-385-8
Molecular formula: C21H25N·HCl
Molecular weight: 327.9

Terbinafine·HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene, which interferes with cell membrane function and wall synthesis.

Additionally, Terbinafine has also been reported to suppress cell proliferation in vitro and in vivo through inhibition of DNA synthesis and apoptosis activation. It has also been noted that by pretreating of cells with a p21 specific antisense oligonucleotide the Terbinafine induced inhibition of cell growth can be reversed.

Certification of analysis

Items	Specifications	Results
Characters
Appearance	White or off-white crystalline powder	White powder
Solubility	Practically insoluble in water and in aceton, soluble in ethanol and in methanol	Complies
Identification
A: IR	The infrared absorption spectrum exhibits maximum only at the same wavelengths as that of the standard sample	Complies
B:	It gives reaction of chlorides	Complies
	Impurity A NMT 0.1%	0.00%
	Impurity B NMT 0.1%	0.01%
	Impurity C NMT 0.1%	0.02%
	Impurity D NMT 0.1%	0.02%
	Any other impurity NMT0.1%	0.05%
	Total of impurity NMT 0.3%	0.15%
Loss on drying	NMT0.5%	0.15%
Sulphated ash	NMT0.1%	0.02%
Assay	99%~101% (dried substance )	99.85%

Function

Terbinafine hydrochloride is an antifungal, which is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue.

Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water.

Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesize.

Company Information

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in lead acetate, diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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