Sulfadiazine 68-35-9 Sulphadiazine Wholesaler

Min.Order / FOB Price:Get Latest Price

100 Kilogram	FOB Price:USD 37.0000 -38.0000

100 Kilogram

FOB Price:USD 37.0000 -38.0000

Min.Order :100 Kilogram
Purity: 99.5%
Payment Terms : L/C,D/A,D/P,T/T,Other

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68-35-9 Sulphadiazine price 68-35-9 Sulphadiazine Factory 68-35-9 Sulphadiazine Wholesaler

Quick Details

Appearance:Yellowish white powder
Application:Sulfadiazine is an antibiotic. Used together with pyrimethamine, it is the treatment of choice for toxoplasmosis. It is a second-line treatment for otitis media, prevention of rheumatic fever, chancro
PackAge:by your need
ProductionCapacity:500|Metric Ton|Month
Storage:Store in a cool, dry, well-ventilated warehouse.
Transportation:by sea or by air

Superiority:

Sulfadiazine is a sulfonamide antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria.It inhibits dihydropteroate synthase (DHPS), which converts a pteridine and 4-aminobenzoic acid to dihydropteroate, an intermediate in folate biosynthesis.Sulfadiazine inhibits recombinant P. carinii DHPS (IC₅₀ = 0.19 μM). It is active against clinical isolates of M. tuberculosis (MIC₉₀ = 10 mg/L) and of N. meningitidis (MICs = 5-2,000 mg/L).Sulfadiazine is also active against A. pleuropneumoniae, S. choleraesuis, S. typhimurium, P. multocida, S. equi, and S. suis (MIC₉₀s = <0.5 mg/ml for all) when used in combination with trimethoprim In vivo, sulfadiazine (40 mg/kg per day) increases survival in a mouse model of lethal T. gondii infection when administered in combination with pyrimethamine Formulations containing sulfadiazine have been used in the treatment of rheumatic fever and various infections, and, in a dual treatment with pyrimethamine, to treat toxoplasmosis.

It is excellent kinds of sulfa drugs with strong antibacterial activity, good efficacy, rapid absorption, slow excretion rate and high plasma concentration. It is clinically used for treating upper respiratory tract infection, Meningococcal meningitis, otitis media, boils carbuncle, puerperal fever, urinary tract infections and acute dysentery and so on.

Details:

Sulfadiazine is an oral sulfonamide anti-bacterial agent. it is a synthetic pyrimidinyl sulfonamide derivative, The chemical classification of sulfadiazine is Sulfonamides.The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfadiazine is used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

Sulfadiazine is used as an antibacterial. It is a short-acting sulfonamide that is commonly used with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome. It is also used to treat newborns with congenital infections and to control acute infections when studying murine models of reactivated toxoplasmosis. It is It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs)

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