1197-18-8 Tranexamic acid exporter In China

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price:USD 220.0000 -225.0000

1 Kilogram

FOB Price:USD 220.0000 -225.0000

Min.Order :1 Kilogram
Purity: 99%min
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

1197-18-8 Tranexamic acid 1197-18-8 Tranexamic acid exporter 1197-18-8 Tranexamic acid In China

Quick Details

Appearance:White Powder
Application:Tranexamic Acid ,a mechanism of work that the validity of the whitening, not only can play excellent cleaning effect, the further reduce melanin, fade melanin generation spots, can prevent ultraviolet
PackAge:AS YOUR NEED
ProductionCapacity:100|Kilogram|Day
Storage: Cool and Dry
Transportation:by sea or air

Superiority:

Tranexamic acid is an inhibitor of fibrinolysis that inhibits the interaction of plasmin with fibrin (IC₅₀ = 3.1 µM in isolated human plasma). It decreases α-naphthylisothiocyanate (ANIT)-induced increases in the expression of the profibrogenic genes Timp1 and Col1a1, but not Itgb6, Tgfβ1, or Tgfβ2, and reduces protein levels of cytokeratin 19 (CK19) and type I collagen in the liver after 28 days in a mouse model of chronic bile duct injury

Fibrinolysis, the cleavage of fibrin by plasmin, is a normal step in the dissolution of fibrin clots after wound repair. Tranexamic acid is an inhibitor of fibrinolysis that blocks the interaction of plasmin with fibrin (IC50 = 3.1 μM). It is a lysine mimetic that binds the lysine binding site in plasmin. Antifibrinolytic agents have value when fibrinolytic activity is abnormally high or when coagulation is impaired.

Details:

Tranexamic Acid is a synthetic derivative of the amino acid lysine with antifibrinolytic activity. With strong affinity for the five lysine-binding sites of plasminogen, tranexamic acid competitively inhibits the activation of plasminogen to plasmin, resulting in inhibition of fibrinolysis; at higher concentrations, this agent noncompetitively inhibits plasmin. This agent has a longer half-life, is approximately ten times more potent, and is less toxic than aminocaproic acid, which possesses similar mechanisms of action.

Product name

Tranexamic acid, plasminogen activation inhibitor
Description

Antifibrinolytic and plasminogen activation inhibitor
Biological description

Antifibrinolytic and plasminogen activation inhibitor. Blocks lysine-binding sites of plasmin and elastase-derived plasminogen fragments (IC₅₀ = 5 mM).
Purity

> 98%
CAS Number

1197-18-8
Chemical structure

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