50-24-8 prednisolone Manufacturer

Min.Order / FOB Price:Get Latest Price

10 Kilogram	FOB Price:USD 395.0000 -400.0000

10 Kilogram

FOB Price:USD 395.0000 -400.0000

Min.Order :10 Kilogram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

50-24-8 prednisolone bulk 50-24-8 prednisolone in stock 50-24-8 prednisolone Manufacturer

Quick Details

Appearance:White to off-white powder
Application:Anti-vertigo and antiemetics and memory therapy
PackAge:AS YOUR NEED
ProductionCapacity:100|Kilogram|Day
Storage:Cool and dry environment
Transportation:by sea or air

Superiority:

Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations

Prednisolone is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and auto-immune conditions. Prednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for which they have a high affinity.

Details:

Prednisolone is a glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone. It has a role as an adrenergic agent, an anti-inflammatory drug, an antineoplastic agent, an immunosuppressive agent, a drug metabolite, an environmental contaminant and a xenobiotic. It is a glucocorticoid, an 11beta-hydroxy steroid, a 21-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It derives from a Delta(1)-progesterone.

Prednisolone can be used to treat severe asthmatic attacks that do not respond to conventional treatment, and it is available as the free alcohol for oral administration. The C-21 sodium phosphate (Hydeltrasol) ester is available for parenteral use.

Catalogue Number	P703740
Chemical Name	Prednisolone
Synonyms	(11β)-11,17,21-Trihydroxy-pregna-1,4-diene-3,20-dione; Metacortandralone; Delta F; Delta1-Hydrocortisone; Hydroretrocortine; Codelcortone; Decaprednil; Predonine; Hydrocortisone EP Impurity A;
Impurity	Hydrocortisone EP Impurity A
CAS Number	50-24-8
Molecular Formula	C??H??O?
Appearance	White to Off-White Solid
Melting Point	>211ºC (dec.)
Molecular Weight	360.44
Storage	-20°C Freezer
Solubility	DMSO (Slightly), Dioxane (Slightly), Methanol (Slightly)
Category	Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	Synthetic corticosteroid; metabolically interconvertible with prednisone. Hydrocortisone EP Impurity A.

View All

Visit Store