High Purity Atorvastatin calcium High Purity Atorvastatin Calcium supplier in China Atorvastatin calcium Manufacturer in china
1.product description
product name: atorvastatin calcium
cas: 134523-03-8
mf: c66h68caf2n4o10
mw: 1155.36
2.physical properties
white or almost white powder,slightly hygroscopic, ordorless. very solutable in acetonitrile or chloroform, soluble in water, very soluble and practically insolutable in ethyl ether
3.specification
test |
standard |
result |
appearance: |
white or almost white powder, slightly hygroscopic, ordorless |
confirms |
very solutable in acetonitrile or chloroform, soluble in water, very soluble and practically insolutable in ethyl ether |
confirms |
|
identification |
(1) ir |
conforms |
(2) hplc |
conforms |
|
water |
nmt 5.0% |
0.6% |
residue on ignition |
nmt 0.2% |
0.1% |
methyl benzenesulfonate |
nmt 0.1% |
undetected |
toluene |
nmt 890ppm (ich) |
102ppm |
chromatographic purity |
(1) laudanosine: nmt 0.5% (2) other individual impurities: nmt 1.0% (3) total impurities: nmt 3.5% |
0.01% 0.38% 1.3% |
isomer ratio |
trans-trans isomer: 5%-6.5% |
5.7% |
|
cis-trans isomer: 34.5%-38.5% |
36% |
|
cis-cis isomer: 55%-60% |
58.2% |
assay |
96%-102% (c65h82n2o18s2 on anhydrous basis) |
100.2% |
residue solvents |
(1) dichloromethane: nmt 600ppm (2) acctonitrile: nmt 410ppm (3) ethyl ether: nmt 5000ppm |
undetected undetected 1739ppm |
result |
confirms to usp34 |
4.application
atorvastatin is a member of the drug class known as statins, used for lowering blood cholesterol. it also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. like all statins, atorvastatin works by inhibiting hmg-coa reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.
5.packing
25kg/drum or as per your requirement
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