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59-43-8 Thiamine chloride Suitable for vitamin B1 deficiency
Items |
thiamine pyrophosphate Specification |
Results |
|
BP2012 |
Appearance |
A white or almost white, crystalline powder or small, colorless crystals |
White crystalline powder |
Identification |
Meet the requirements |
Comply |
|
Appearance of solution |
Clear, not more intense than Y7 or GY7 |
Comply |
|
pH |
2.7-3.3 |
3.0 |
|
Water |
≤ 5.0% |
1.60% |
|
Sulphated ash |
≤ 0.1% |
0.06% |
|
Heavy metals |
≤ 20ppm |
<10ppm |
|
Sulphates |
≤ 300ppm |
Comply |
|
Any impurity |
≤0.40 % |
0.13% |
|
Total impurities |
≤1.0% |
0.41% |
|
Assay |
98.0%-101.0% |
99.4% |
|
USP34 |
Identification |
Meet the requirements |
Comply |
pH |
2.7-3.4 |
3.0 |
|
Water |
≤ 5.0% |
1.60% |
|
Residue on ignition |
≤ 0.2% |
0.06% |
|
Absorbance of solution |
≤ 0.025% |
Comply |
|
Limit of nitrate |
Meet the requirement |
Comply |
|
Chromatographic purity |
Meet the requirement |
Comply |
|
Residual solvent Methanol Ethanol |
≤ 0.3% ≤ 0.5% |
Not detected 0.03% |
|
Assay |
98.0%-102.0% |
99.4% |
|
Conclusion: All the results conform to the BP2012 and USP34. |
(1) it is mainly used for the prevention and treatment of vitamin B1 deficiency and beriberi or Wernickes encephalopathy. It is also used for peripheral neuritis, myocarditis, dyspepsia, congestive heart failure and other auxiliary treatments. Vitamin B1 supplementation: including burns, fever, long-term chronic infection patients; Patients with malabsorption syndrome with hepatobiliary diseases (such as alcoholism with liver cirrhosis), intestinal diseases (such as celiac disease, persistent diarrhea, etc.), post-gastrectomy, hyperthyroidism, and hemodialysis; Malnutrition caused by prolonged parenteral nutrition or inadequate intake, heavy manual workers, pregnant women and lactating women.
(2) AIDS nutrition support, alzheimer's disease, epilepsy, oral ulcer, diabetes.
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