Min.Order / FOB Price:Get Latest Price
100 Kilogram |
FOB Price:USD 113.0000 -115.0000 |
62893-20-3 Cefoperazone sodium 62893-20-3 Cefoperazone sodium Hot Sale 62893-20-3 Cefoperazone sodium price
Cefoperazone Sodium is an antimicrobial agent useful for prevention of postoperative infection. Cefoperazone sodium is also an inhibitor of inactivation of α(1)-antitrypsin. As a cephalosporin antibiotic, Cefoperazone sodium has been studied in upper and lower respiratory tract infection treatments, as well as gynecological and skin infection treatments. Cefoperazone sodium is also being investigated for its use in the the treatment of bacteremia.
Cefoperazone sodium is a third-generation, antipseudomonalcephalosporin that resembles piperacillinchemically and microbiologically. It is active against manystrains of P. aeruginosa, indole-positive Proteus spp.,Enterobacter spp., and S. marcescens that are resistant tocefamandole. It is less active than cephalothin againstGram-positive bacteria and less active than cefamandoleagainst most of the Enterobacteriaceae. Like piperacillin,cefoperazone is hydrolyzed by many of the β-lactamasesthat hydrolyze penicillins. Unlike piperacillin, however, itis resistant to some (but not all) of the β-lactamases thathydrolyze cephalosporins.Cefoperazone is excreted primarily in the bile. Hepaticdysfunction can affect its clearance from the body.
Cefoperazone Sodium is the sodium salt form of cefoperazone and a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. It is marketed by Pfizer under the name Cefobid. Cefoperazone sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis. It is one of few cephalosporin antibiotics effective in treating Pseudomonas bacterial infections which are otherwise resistant to these antibiotics.
Structure | |
Catalog No. | SS-7542 |
Name | Cefoperazone sodium |
CAS number | 62893-20-3 |
Related CAS | 1094606-34-4, 62893-19-0, 62893-20-3 |
MFCD number | MFCD07793331 |
Purity | 95% |
Formula | C25H26N9O8S2.Na |
FW | 667.7 |
Storage | Room temperature |
Shipping | Normal |
CAS NO:57-83-0
CAS NO:57-83-0
CAS NO:57-83-0
CAS NO:57-83-0
CAS NO:57-83-0
CAS NO:57-83-0
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View