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factory 1208319-27-0 Oclacitinib maleate Good Supplier In China Oclacitinib maleate on hot selling
GIHI CHEMICALS exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, GIHI CHEMICALS is your best choice. pls contact with us freely for getting detailed product specifications, product tech. date sheet, coa and msds, prices, delivery time and payment terms. as a leading manufacturer and supplier of chemicals in china, GIHI CHEMICALS not only supply popular chemicals, but also GIHI CHEMICALS's r&d center offer custom synthesis services. GIHI CHEMICALS can provide different quantities of custom synthesis chemicals in lab, plant and industrial.
product name: oclacitinib maleate(pf-03394197)
synonyms: oclacitinib maleate(pf-03394197);n-methyl-1-((1r,4r)-4-(methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide maleate;oclacitinib maleate;pf 03394197-11;oclacitinib meleate
cas: 1208319-27-0
mf: c15h23n5o2s.x(c4h4o4)
Oclacitinib maleate is a novel JAK inhibitor. Oclacitinib is most potent at inhibiting JAK1 (IC50=10 nM).
IC50 & Target: IC50: 10 nM (JAK1), 18 nM (JAK2), 99 nM (JAK3), 84 nM (TYK2)
Oclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Oclacitinib inhibited JAK family members by 50% at concentrations (IC50 's) ranging from 10 to 99 nM and did not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000 nm). Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31) at IC50 's ranging from 36 to 249 nM.
GIHI CHEMICALS, dedicated to the development, production and marketing of chemicals. we are a leading manufacturer and supplier of chemicals in china.
manufacturing base: the company has some manufacturing base in zhejiang, jiangsu and shandong provide. these bases focus on production and contract manufacturing.
strong quality control system: strength of our ethical commitment to quality control and quality assurance systems firmly based on iso standard. qa and qc used in the whole process of raw material control, process control and finished product quality inspection.
sales agent: GIHI CHEMICALS is authorized by many chinese chemical manufacturers as universal agency and international area agency. GIHI CHEMICALS has established very good cooperation and business relations with hundreds of chinese qualified manufacturers by long time business intercourse.
rich experience in sales: 1000 square meters of office space with independent property rights, sales team . our customers throughout the world, especially the world-renowned companies, such as bachem, basf, celanese, corden,dow,evonik, genzyme,henkel, merck,roche,sanofi,solvay.
flexible payment terms: various payment terms such as l/c,d/p,d/a and t/t will be accepted. special notice: GIHI CHEMICALS never require customers to remit payment to a personal account. beware of being cheated.
F.A.Q
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable.
A:Sample needs 3-5 days, mass production time needs 1-2 weeks for order quantity more than
A: Low MOQ, 10-100g for sample checking is available
A: We usually ship by DHL, UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional.
A: Firstly let us know your requirements or application.
Secondly We quote according to your requirements or our suggestions.
Thirdly customer confirms the samples and places deposit for formal order.
Fourthly We arrange the production.
A: Yes. Please inform us formally before our production and confirm the design firstly based on our sample.
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