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1 Kilogram |
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184177-83-1 2-[(1S,2S)-1-Ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one Posaconazole intermediate
Description |
White to off- White powder |
Conforms |
|
Identification |
IR |
IR spectrum of sample is the same as working standard |
Conforms |
HPLC |
HPLC RT of the sample is the same as the working standard |
Conforms |
|
Melting point |
165.0°C~169.0°C |
165.8°C~167.0°C |
|
Optical rotation |
-23°~-29° |
-27.4° |
|
Loss on drying |
NMT 1.0 % |
0.17% |
|
Residue on ignition |
NMT 0.1 % |
0.03% |
|
Heavy metals |
NMT 20ppm |
Conforms |
|
Related substances |
|||
Impurity A |
NMT 0.1 % |
Not detected |
|
Impurity B |
NMT 0.1 % |
Not detected |
|
Impurity C |
NMT 0.1 % |
0.02% |
|
Single impurity |
NMT 0.2 % |
0.17% |
|
Total impurity |
NMT 1.0 % |
0.60% |
|
Assay |
NLT 99.0% |
99.0% |
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