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Berberine hydrochloride Basic information |
Product Name: | Berberine hydrochloride |
Synonyms: | TIMTEC-BB SBB006488;NATURAL YELLOW 18 CHLORIDE;NATURAL YELLOW 18;UMBELLATINE;5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE;BERBERINE HCL;BERBERINE HYDROCHLORIDE;BERBERIN HCL |
CAS: | 633-65-8 |
MF: | C20H18ClNO4 |
MW: | 371.81 |
EINECS: | 211-195-9 |
Product Categories: | Natural Plant Extract;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Plant extracts;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
Mol File: | 633-65-8.mol |
Berberine hydrochloride Chemical Properties |
mp | 204-206 °C (dec.) |
Water Solubility | SOLUBLE IN COLD WATER |
EPA Substance Registry System | Benzo[g]-1,3-benzodioxolo[ 5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride(633-65-8) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 20/21/22-36/37/38 |
Safety Statements | 24/25-36-26 |
RIDADR | 1544 |
WGK Germany | 2 |
RTECS | DR9866400 |
F | 3-10 |
HazardClass | 6.1(b) |
PackingGroup | III |
MSDS Information |
Provider | Language |
---|---|
Natural Yellow 18 | English |
SigmaAldrich | English |
Berberine hydrochloride Usage And Synthesis |
Chemical Properties | yellow crystalline powder |
Usage | antiarrhythmic, alpha2 agonist, anticonvulsant, antiinflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, immunostimulant |
Usage | An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Al so inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation o f chemotherapeutic drugs. |
Usage | An ingredient in some commercial eyewash products. |
Berberine hydrochloride Basic information |
Product Name: | Berberine hydrochloride |
Synonyms: | TIMTEC-BB SBB006488;NATURAL YELLOW 18 CHLORIDE;NATURAL YELLOW 18;UMBELLATINE;5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE;BERBERINE HCL;BERBERINE HYDROCHLORIDE;BERBERIN HCL |
CAS: | 633-65-8 |
MF: | C20H18ClNO4 |
MW: | 371.81 |
EINECS: | 211-195-9 |
Product Categories: | Natural Plant Extract;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Plant extracts;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
Mol File: | 633-65-8.mol |
Berberine hydrochloride Chemical Properties |
mp | 204-206 °C (dec.) |
Water Solubility | SOLUBLE IN COLD WATER |
EPA Substance Registry System | Benzo[g]-1,3-benzodioxolo[ 5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride(633-65-8) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 20/21/22-36/37/38 |
Safety Statements | 24/25-36-26 |
RIDADR | 1544 |
WGK Germany | 2 |
RTECS | DR9866400 |
F | 3-10 |
HazardClass | 6.1(b) |
PackingGroup | III |
MSDS Information |
Provider | Language |
---|---|
Natural Yellow 18 | English |
SigmaAldrich | English |
Berberine hydrochloride Usage And Synthesis |
Chemical Properties | yellow crystalline powder |
Usage | antiarrhythmic, alpha2 agonist, anticonvulsant, antiinflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, immunostimulant |
Usage | An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Al so inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation o f chemotherapeutic drugs. |
Usage | An ingredient in some commercial eyewash products. |
Founded in Chengdu China in 2008 , Hongyi is a professional manufacturer and distributor of plant extracts for the cosmetic, nutritional and pharmaceutical industries .
Our main products are Polygonum Cuspidatum Extract (Resveratrol), Berberine HCL, Baicalin Extract, Andrographis Extract, Salvia Extract, Forsythia Extract, Chlorogenic Acid, Ursolic Acid, Luteolin, Hesperidin, Ginkgo Biloba Extract, Chuanhuning, etc.
Specification of Berberine
|
|
Botanical Source: |
Phellodendron amurense Rupr. |
Part used: |
Bark |
Specification: |
98% |
Item |
SPECIFICATION |
Description: |
|
Appearance |
Yellow crystalline powder |
Flavor & Odor |
Characteristic |
Particle size |
100% pass 80 mesh |
Physical: |
|
Loss on Drying |
≤5.0% |
Bulk density |
40-60g/100ml |
Sulphated Ash |
≤5.0% |
GMO |
Free |
General Status |
Non-irradiated |
Chemical: |
|
Pb |
≤3mg/kg |
As |
≤1mg/kg |
Hg |
≤0.1mg/kg |
Cd |
≤1mg/kg |
Assay: |
|
Berberine |
≥98% |
Microbial: |
|
Total microbacterial count |
≤1000cfu/g |
Yeast & Mold |
≤100cfu/g |
E.Coli |
Negative |
Staphylococcus aureus |
Negative |
Salmonella |
Negative |
Enterobacteriaceaes |
Negative |
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