Abacavir EP Impurity D with high purity>98% in stock CAS 783292-37-5
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| 10 Milligram |
Negotiable |
- Min.Order :10 Milligram
- Purity: >98%
- Payment Terms : T/T
Keywords
783292-37-5 Abacavir Abacavir EP Impurity D
Quick Details
- Appearance:Off-White Solid
- Application:For lab research use only
- PackAge:Moisture-proof packaging
- ProductionCapacity:1|Gram|Week
- Storage:Store at 2-8℃, dry, in dark
- Transportation:By air
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Details:
Product Name: Abacavir EP Impurity D
Chemical Name: ((1R,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methanol
Molecular Formula: C14H18N6O
Molecular Weight: 286.33
CAS#: 783292-37-5
Purity: >98%
Appearence: Off-White Solid
Price: Negotiable
Available Document: COA, HPLC/GC, HNMR, qNMR, MS Spectrum
Payment Term: Payment in advance by T/T.
Shipment: Package will dispatched in 7-15 days(According to the date of payment) by air.
Trade Term: EXW, FOB, CFR, DDU, DDP, ect.
((1R,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methanol (Abacavir EP Impurity D) is an impurity of Abacavir . Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Reference:
(1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012)
(2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)
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