Dexamethasone

Longfine pharma specializes in controling the quality and reducing the impurities of  Epinephrine Bitartrate . Our Epinephrine Bitartrate  is with the best quality and the most competitive price in China.

Introduction

       Dexamethasone is a type of corticosteroid medication.It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, and along with antibiotics in tuberculosis.In adrenocortical insufficiency, it should be used together with a medication that has greater mineralocorticoid effects such as fludrocortisone.In preterm labor, it may be used to improve outcomes in the baby.It may be taken by mouth, as an injection into a muscle, or intravenously.The effects of dexamethasone are frequently seen within a day and last for about three days.

Function

Anti-inflammatory

Dexamethasone is used to treat many inflammatory and autoimmune conditions, such as rheumatoid arthritis and bronchospasm.Idiopathic thrombocytopenic purpura, a decrease in numbers of platelets due to an immune problem, responds to 40 mg daily for four days; it may be administered in 14-day cycles. It is unclear whether dexamethasone in this condition is significantly better than other glucocorticoids.

Cancer

People with cancer undergoing chemotherapy are often given dexamethasone to counteract

certain side effects of their antitumor treatments. Dexamethasone can increase the 

antiemetic effect of 5-HT3 receptor antagonists, such as ondansetron.The exact mechanism of this interaction is not well-defined, but it has been theorized that this effect may be

due to, among many other causes, inhibition of prostaglandin synthesis, anti-inflammatory 

effects, immunosuppressive effects, or a combination of the aforementioned.

 Endocrine

Dexamethasone is the treatment for the very rare disorder of glucocorticoid resistance.

In adrenal insufficiency and Addison's disease, dexamethasone is prescribed when the patient does not respond well to prednisone or methylprednisolone.

It can be used in congenital adrenal hyperplasia in older adolescents and adults to suppress ACTH production. It is typically given at night.

Pregnancy

Dexamethasone may be given to women at risk of delivering prematurely to promote 

maturation of the fetus' lungs. This has been associated with low birth weight, although

not with increased rates of neonatal death.

High-altitude illnesses

Dexamethasone is used in the treatment of high-altitude cerebral edema (HACE), as well

as high-altitude pulmonary edema (HAPE). It is commonly carried on mountain-climbing

expeditions to help climbers deal with complications of altitude sickness.

Vomiting

Dexamethasone and ondansetron are more effective than ondansetron alone in preventin postoperative nausea and vomiting.