142340-99-6 Adefovir dipivoxil Adefovir dipivoxil manufacturer
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1.Product description
Product Name: Adefovir dipivoxil
CAS: 142340-99-6
MF: C20H32N5O8P
MW: 501.47
EINECS: 200-001-8
2.Physical properties
Adefovir dipivoxil is a white to off-white crystalline powder with an aqueous solubility of 19 mg/mL at pH 2.0 and 0.4 mg/mL at pH 7.2. It has an octanol/aqueous phosphate buffer (pH 7) partition coefficient (log p) of 1.91.
3.Specification
Description:crystalline powder
Melting range:129°C~132°C
Loss on drying≤0.5%
Specific rotation:-58°~-62°(C=1,in CH3OH)
Sulphated ash≤0.1%
Heavy metals≤10ppm
Chlorides≤0.02%
Sulfates≤0.02%
Fluorine:14.7%~17.9%
Residual solvent
Methanol ≤0.2%
Isopropanol ≤0.2%
Ethyl acetate≤0.2%
Chloroform ≤0.2%
Related substances(HPLC)
Single impurity ≤0.2%
Total impurities ≤0.5%
Assay≥99.5%
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