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Benazepril hydrochloride 99% Benazepril hydrochloride Benazepril hydrochloride 86541-74-4
Introduction
Benazepril hydrochloride is the main ingredient in benazepril hydrochloride tablets.The mechanism of action is that it can inhibit the activity of angiotensin-converting enzyme, which can relieve a series of symptoms caused by angiotensin-induced symptoms (increased blood pressure, excitatory heart rate caused by vasodilation, insufficient cardiac output blood volume, etc.).
Application
Benazepril hydrochloride is used in the treatment of hypertension and congestive heart failure
Xi'an Kono chem co.Ltd.,founded in 2014,is a holding enterprise of Hong Kong PIONEER BIOTECH GROUP.It is an export-oriented
manufacturring enterprise supported by the Ministry of Commerce.
Kono chem is located in Xi'an,Shaanxi Province,equipped with a number of engineers inPharmaceutical,Nutrition,Bioengineering,commit-ted themselves to create products that meet customer requirments.At present,Kono's main products cover pharmaceutical,food,cosmetics
scientific research.
Item |
Specification |
Result |
Appearance |
White or almost white crystalline powder,hygroscopic |
Complies |
Identification |
The spectra of the sample and reference standard |
Complies |
Infrared Idntificatioin |
Should be comparable |
|
Enantiomeric Purity |
NMT 0.1% |
Not detected |
Impurity A |
|
|
Related Substances |
|
|
Impurity B |
NMT 0.5% |
<0.05% |
Impurity(C+D+E+F+G) |
NMT 0.3%+ NMT 0.2%+ NMT 0.2%+ NMT 0.2% |
Not detected |
Impurity G |
NMT 0.2% |
0.05% |
Any unspecified Impurity |
NMT 0.1% |
Not detected |
Total Impurities |
NMT 2.0% |
0.05% |
Residual solvents |
|
|
Ethanol |
NMT 0.5% |
0.03% |
Ethyl Acetate |
NMT 0.5% |
0.3% |
Toluene |
NMT 0.089% |
Not detected |
Sulfated Ash |
NMT 0.10% |
0.10% |
Loss on Drying |
NMT 1.5% |
0.087% |
Microbial Limit |
||
TAMC |
NMT1000cfu/g |
<10cfu/g |
TYMC |
NMT100cfu/g |
<10cfu/g |
Escherichia coli |
Can not be detected/g |
Not detected/g |
Assay |
97.5~102.0%(Dried substance) |
99.2% |
Conclusion:The product complies as the EP in the above tests |
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