DHEA high purity 53-43-0 wholesale favourable price of DHEA
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| 1 Kilogram |
FOB Price: USD 230.0000 |
- Min.Order :1 Kilogram
- Purity: 99%MIN
- Payment Terms : T/T,,MoneyGram,Other
Keywords
DHEA high purity favourable price of DHEA 53-43-0 wholesale
Quick Details
- Appearance:White fine powder
- Application:Medical Intermediate
- PackAge:Drum or Aluminum Foil Bag
- ProductionCapacity:200|Metric Ton|Month
- Storage:Cool and dry place
- Transportation:prompt delivery after payment confirmed by air courier or by sea
Superiority:
DHEA high purity
53-43-0 wholesale favourable price of DHEA
| Product Name |
Dehydroepiandrosterone |
|
Synonyms |
DHEA; Prasterone; Androstenolone; Dehydroisoandrosterone; trans-Dehydroandrosterone; Hydroxyandrost-5-en-17-one |
|
CAS NO. |
53-43-0 |
|
EINECS |
200-175-5 |
|
Molecular Formula |
C19H28O2 |
|
Molecular Weight |
288.43 |
|
Specifications: |
|
|
Standard |
Assay ≥99% |
|
Appearance |
White crystalline powder |
|
Melting Point |
146-151℃ |
Introduction
Dehydroepiandrosterone (DHEA) is a multifunctional steroid that has been implicated in a broad range of biological effects in humans and other mammals. Together with its sulfate ester (DHEAS), it is the most abundant steroid in humans. DHEA is produced by adrenal glands, but also sythesized de novo in the brain.It acts on the androgen receptor both directly and through its metabolites, which include androstenediol and androstendione, which can undergo further conversion to produce the androgen and the estrogens estrone and estradiol.
DHEA is also a potent sigma-1 agonist. It is considered a neurosteroid DHEA is essential to sustain life, and there are numerous health benefits to having healthy levels of natural DHEA. Dr. Arthur Schwartz of the Temple University School of Medicine says that "DHEA appears to block the growth of carcinogens".
Studies have shown that DHEA is useful in patients with systemic lupus erythematosus. An application of the evidence was discussed by the U.S. Food and Drug Administration in 2001 and is available online.
This review also shows that cholesterol and other serum lipids decrease with the use of DHEA (mainly a decrease in HDL-C and triglycerides can be expected in women)。
Details:
Functional efficacy
1. Prevention and treatment of obesity DHEA has a mimetic thyroid effect, which can inhibit food and fat intake and reduce fat accumulation. DHEA is related to anti-glucocorticoids and can prevent and treat obesity.
2. Anti-diabetic DHEA has the effects of improving glucose tolerance, increasing insulin levels and anti-diabetic.
3. Anti-cortical disease DHEA can enhance the activity of the endocrine system, reduce the level of cortisol, and play a role in resisting various pathological processes.
4. Anti-cancer DHEA has a certain effect on preventing and inhibiting tumor growth,
5. The effect of delaying aging, and the incidence of senile diseases related to the decline of DHEA also increases.
6. Immune response DHEA can restore the impaired immune response and improve the immune function of T cells and B cells. DHEA plays an important role in improving the physiological activity of insulin-like growth factor (IGF-1) and is a potentially beneficial drug for the treatment of immunodeficiency. 7. Impact on bone DHEA itself cannot directly and independently affect the growth and differentiation of human osteoblasts, but it can achieve the growth and differentiation of osteoblasts by affecting the changes of 1,25-dihydroxyvitamin D3. 8. Protein metabolism DHEA is a protein assimilation hormone, which can promote protein synthesis. 9. Other aspects DHEA has done extensive clinical research on the treatment of menopausal syndrome, scleroderma, coronary heart disease, gout, psoriasis, and AIDS.
Specifications
|
Test |
Specifications |
Result |
|
Assay by HPLC: |
98.0% |
99.8% |
|
Appearance: |
White or white-like crystalline powder |
Complies |
|
Odor & taste: |
Odorless |
Complies |
|
Mesh size: |
98% pass 200mesh |
Complies |
|
Melting point: |
168℃ |
149-151° |
|
Specific rotation |
12-15° |
13.5° |
|
Loss on drying %: |
≤0.5% |
0.23% |
|
Heavy metals PPM: |
<20ppm |
Complies |
|
Microbiology: Total Plate Count: Yeast & Mold: E.Coli: S. Aureus: Salmonella: |
<1000cfu/g <100cfu/g Negative Negative Negative
|
Complies Negative Complies Complies Complies |
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