Mesalazine 5-Aminosalicylic acid 5-Aminosalicylic acid, 98.5%, IKK inhibitor
5-Aminosalicylic acid Basic information
Overview Indication Mode of action Pharmacokinetics Adverse reactions and toxicity References
Product Name: 5-Aminosalicylic acid
Synonyms: 5-Aminosalicylic acid, 98.5%, IKK inhibitor;2-HYDROXY-5-AMINOBENZOIC ACID;3-Carboxy-4-hydroxyaniline;5-AMINO-2-HYDROXYBENZOIC ACID;5-AMINOSALICYLIC ACID;5-ASA;5-AS;rowasa
CAS: 89-57-6
MF: C7H7NO3
MW: 153.14
EINECS: 201-919-1
Product Categories: API;CITANEST;Pharmaceuticals;Carboxylic Acids;Aromatics;Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Carboxylic Acids;Phenyls & Phenyl-Het;Organic acids;Various Metabolites and Impurities;Fendosal;Intermediates & Fine Chemicals;Phenyls & Phenyl-Het;Fluorescent;FINE Chemical & INTERMEDIATES;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Metabolites & Impurities
Mol File: 89-57-6.mol
5-Aminosalicylic acid Structure
5-Aminosalicylic acid Chemical Properties
Melting point 275-280 °C (dec.)(lit.)
Boiling point 276.03°C (rough estimate)
density 1.3585 (rough estimate)
refractive index 1.5500 (estimate)
Fp 279-281°C
storage temp. 2-8°C
solubility Soluble in dimethyl sulfoxide.
form tablets
pka 2.74, 5.84(at 25℃)
color off-white to gray
PH 4.0-4.1 (0.8g/l, H2O, 20℃)
PH Range Non-B uorescence (3.1) to light green B uorescence (4.4)
Water Solubility <0.1 g/100 mL at 21 ºC
Decomposition 279-281 ºC
Merck 14,5904
BRN 2090421
Stability: Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
Major Application Detergent, hair dyes, prevention of colorectal cancer, treating inflammatory bowel disease, autoimmune disorders, gastrointestinal inflammation, chemokine-mediated diseases, mucosal tissue disorder, sleep disorders, rectoanal tenesmus, ulcerative colitis
InChIKey KBOPZPXVLCULAV-UHFFFAOYSA-N
CAS DataBase Reference 89-57-6(CAS DataBase Reference)
NIST Chemistry Reference Mesalamine(89-57-6)
EPA Substance Registry System Benzoic acid, 5-amino-2-hydroxy- (89-57-6)
Ality Chemical, established in 2007, is a comprehensive Chemical Production&Supply Group with Patent Technology as its core. Ality Chemical operates sales branches in Shanghai, Xiamen and Hongkong, including production bases in Xinjiang(90,000 square meters), Hebei(40,000 square meters), Jiangsu(36,000 square meters) and Fujian(31,000 square meters) provinces.
Ality Chemical mainly provides Life Science Series, Fine Intermediates, Chemical Additives and Custom Manufactures including OEM and R&D Services.
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