Amphotericin B Amphotericin B 13C6 Amphotericin B, Pharma
Amphotericin B Basic information
Pharmacology and mechanism of action Indications Side effects Contraindications and precautions Preparations Interactions Polyene antifungal antibiotics Pharmacokinetic Indications Side effects Drug interactions Amphotericin B liposome Amphotericin B and Nephrotoxicity Chemical properties Uses Production methods Category References Acute toxicity Flammability and hazard characteristics Storage and transport properties Fire extinguishing agent
Product Name: Amphotericin B
Synonyms: FUNGIZONE;FUNGIZONE(R);ABELCET;AMBISOME;AMPHOTERCIN B;AMPHOTERICIN B;AMPHOTERICIN B SOLUBILIZED;AMPHOTERICIN B, SOLUBLE
CAS: 1397-89-3
MF: C47H73NO17
MW: 924.08
EINECS: 215-742-2
Product Categories: Miscellaneous Natural Products;Antibiotic Explorer;AM to AQAntibiotics;MLS;A;Alphabetic;Chemical Structure;Inhibitors;Antibiotics A to;Antibiotics A-FAntibiotics;AntibioticsAntibiotics;AntifungalAntibiotics;Cell Culture;Intermediates & Fine Chemicals;Pharmaceuticals;ABELCET;antibiotic;Carbohydrates & Derivatives;Chiral Reagents;Antifungal;Chemical Structure Class;Interferes with Cell Membrane Permeability (Ionophores)Antibiotics;Mechanism of Action;Polyenes;Reagents and Supplements;Spectrum of Activity;APIs
Mol File: 1397-89-3.mol
Amphotericin B Structure
Amphotericin B Chemical Properties
Melting point >170°C
alpha D24 +333° (acidic DMF); -33.6° (0.1N methanolic HCl)
Boiling point 804.34°C (rough estimate)
density 1.34
refractive index 1.5280 (estimate)
storage temp. 2-8°C
solubility sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20 #x00b0;C. Stable at 37 #x00b0;C for 3 days.
pka pKa ~5.7(DMF/H2O) (Uncertain)
form powder
color yellow
Water Solubility <0.1 g/100 mL at 21 ºC
Sensitive Moisture & Light Sensitive
Merck 13,590
BRN 78342
Stability: Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
InChIKey APKFDSVGJQXUKY-INPOYWNPSA-N
CAS DataBase Reference 1397-89-3(CAS DataBase Reference)
EPA Substance Registry System Amphotericin B (1397-89-3)
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Ality Chemical mainly provides Life Science Series, Fine Intermediates, Chemical Additives and Custom Manufactures including OEM and R&D Services.
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