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Chloramphenicol (-)-Chloramphenicol threo-Chloramphenicol
Chloramphenicol Basic information
Description Chemical Properties Uses Antimicrobial Spectrum Mechanism of action Pharmacokinetics Indications resistance Drug interactions Adverse reactions and precautions Methods of production
Product Name: Chloramphenicol
Synonyms: ,[theta-(theta,theta)]-;[R-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]ethanamide;2,2-dichloro-n-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-acetamid;2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-,[R-(R*,R*)]-Acetamide;2,2-dichloro-n-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamid;Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl);Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-;Acetamide, 2,2-dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
CAS: 56-75-7
MF: C11H12Cl2N2O5
MW: 323.13
EINECS: 200-287-4
Product Categories: Pyridines;Active Pharmaceutical Ingredients;Antibiotics for Research and Experimental Use;Biochemistry;Others (Antibiotics for Research and Experimental Use);Antibiotic Explorer;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;API;Pharmaceutical intermediates;CHLOROMYCETIN;antibiotic;Chiral Reagents;Pharmaceutical intermediate
Mol File: 56-75-7.mol
Chloramphenicol Structure
Chloramphenicol Chemical Properties
Melting point 148-150 °C(lit.)
alpha 19.5 º (c=6, EtOH)
Boiling point 644.9±55.0 °C(Predicted)
density 1.6682 (rough estimate)
refractive index 20 ° (C=5, EtOH)
Fp 14 °C
storage temp. 2-8°C
solubility absolute ethanol: soluble5-20mg/mL (as a stock solution)
pka 11.03±0.46(Predicted)
form powder
color white
Water Solubility 2.5 g/L (25 º C)
Merck 14,2077
BRN 2225532
InChIKey WIIZWVCIJKGZOK-RKDXNWHRSA-N
CAS DataBase Reference 56-75-7(CAS DataBase Reference)
NIST Chemistry Reference Chloramphenicol(56-75-7)
IARC 2A (Vol. Sup 7, 50) 1990
EPA Substance Registry System Chloramphenicol (56-75-7)
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