Bulk supply Donepezil Hydrochloride CAS No.120011-70-3

Bulk supply Donepezil Hydrochloride CAS No.120011-70-3

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price:USD 19.0000 -20.0000

1 Kilogram

FOB Price:USD 19.0000 -20.0000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : T/T,,MoneyGram,Other

Keywords

120011-70-3 Donepezil Hydrochloride Donepezil Hydrochloride supplement

Quick Details

Appearance:white powder
Application:FADE BLACK FRECKLE, regulate endocrine, improve sleep, antioxidant
PackAge:drum/25 kgs
ProductionCapacity:100|Metric Ton|Month
Storage:dry cool
Transportation:car/ship/air

Superiority:

1.We supply our existing products steadily and provide continuous and perfect aftersales service to help our customers solve all kinds of questions during the process of using the products.

2.We pay close attention to the international and domestic market trends constantly, enriching the latest products reserve for future use to provide customers with more updated .

3.We continue to research and practice to improve product performances to make our products more in line with customer application requirements.

4.We also provide full customize service such as research and develop, laboratorysmall-scale trial test, scale up production and cost accounting according to the chemical structure, quantityand quality requirements provided by our customers.

1. the most competitive prise

2. the best quality

3. efficient service

4. the best package

Details:

Aricept was launched in Canada, Germany, the UK and the US for treatment of mild to moderate Alzheimer’s disease and dementia. It was prepared in three steps beginning with the condensation of 5,6-dimethoxy-1-indanone with 1-benzylpiperidine- 4-carboxaldehyde. Aricept is a reversible, non-competitive inhibitor of acetylcholinesterase. It is 570-1250 times more selective for acetylcholinesterase than for butylcholinesterase. It has a greater affinity for brain over peripheral acetylcholinesterase with no inhibition in cardiac and smooth muscle, but with slight effects in striated muscle. Aricept inhibited all three isozymes (type A, G2 and G4) of acetylcholinesterase thereby delaying the decline of cholinergics found in the AD brain and slowing the loss of cognitive abilities. It has a 60-70 hr half-life, readily penetrates the CNS, and is 100% bioavailable through the gut with no hepatotoxicity.

Melting point	220-222°C
storage temp.	-20°C Freezer
form	powder
color	white to off-white
Merck	14,3419
InChIKey	XWAIAVWHZJNZQQ-UHFFFAOYSA-N
CAS DataBase Reference	120011-70-3(CAS DataBase Reference)