Amadis Chemical offer CAS#50-76-0;CAT#A828284 High purity Actinomycin D Actinomycin D Manufacturer in china
Actinomycin D Basic information |
Product Name: | Actinomycin D |
Synonyms: | 2-Amino-N,N'-bis[hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide;Actinomycin D, Actinomycin IV, Actinomycin C1, Dactinomycin;Dactinomycin, DTM;Actinomycin C1, Dactinomycin;Actactinomycin A IV;Cosmogen;actinomycin7;actinomycinaiv |
CAS: | 50-76-0 |
MF: | C62H86N12O16 |
MW: | 1255.42 |
Actinomycin D Chemical Properties |
Melting point | 251-253 °C |
Boiling point | 848°C (rough estimate) |
density | 1.0757 (rough estimate) |
refractive index | 1.5700 (estimate) |
Fp | 87℃ |
storage temp. | 2-8°C |
solubility | ethanol, DMSO: Stable in aqueous solutions at 2-8 °C.soluble |
form | powder |
color | red, powder |
Safety Information |
Hazard Codes | T+ |
Risk Statements | 28-61-40-45-26/27/28 |
Safety Statements | 53-36/37/39-45-1-36/37-28-22 |
RIDADR | UN 3462 6.1/PG 2 |
WGK Germany | 3 |
RTECS | AU1575000 |
F | 8-10-21 |
HazardClass | 6.1(a) |
PackingGroup | II |
HS Code | 29419000 |
Actinomycin D Usage And Synthesis |
Chemical Properties | red crystalline powder |
Chemical Properties | Actinomycin D is a combustible, bright red crystalline solid. |
Originator | Cosmegen,Merck Sharp and Dohme,US,1965 |
Uses | Antibiotic substance belonging to the actinomycin complex, produced by several Streptomyces spp. Antineoplastic |
Uses | An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. |
Uses | antineoplastic, intercalating agent |
Uses | Actinomycin D is the most studied member of a family of unique bicyclic depsipeptides produced by several Streptomyces species. The depsipeptides are linked by a heterocyclic benzoxazone "anchor" that gives the metabolites a highly distinctive red/orange colour. Actinomycin D exhibits potent antibiotic and antitumour activity via DNA intercalation leading to the inhibition of nucleic acid synthesis. Tumour cell death has been demonstrated to occur by apoptosis. |
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