Pentostatin

Pentostatin

Pentostatin

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 99.0%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Reliable quality 53910-25-1 PENTOSTATIN CL-67310465 co-vidarabine

Quick Details

  • Appearance:Detailed see specifications
  • Application:An adenosine deaminase inhibitor used as an anti-cancer therapeutic drug. Shown to be effective in the treatment of hairy cell leukemia as well as having use in the treatment of other types of cancer
  • PackAge: According to customer requirements
  • ProductionCapacity:1|Kilogram|Day
  • Storage:Store under shade and cool environment without direct sunlight after sealing.
  • Transportation:During the transportation process, all containers should be free of leak, falling, collapse and damage. All products transported in tanker should be kept no less than 25℃ to facilitate.

Superiority:

Hangzhou Benoy Chemical Co., Ltd is a scientific and technological enterprise dedicated to the R & D, production and operation of chemical raw materials, pharmaceutical intermediates and APIs. At present, the company has one R & D center and two production bases. The company has more than 10 full-time personnel engaged in the research and development of APIs and pharmaceutical intermediates, including 2 with doctor's degree, 5 with master's degree, 2 with Professor of Zhejiang University of technology as the chief consultant of the company, with strong scientific research force and rich practical experience. The laboratory is equipped with advanced ultra-high performance liquid chromatography, gas chromatography and relatively complete conventional experimental equipment. Many products have been successfully developed and put into industrial production. The company adheres to the quality and environment policy of "customer first, continuous innovation", and excellent products win good market reputation for the company. At present, the products are exported to Europe, the United States, Southeast Asia and other countries and regions. It is the company's business philosophy to guide technology with information, guarantee quality with technology and win market with quality. The company will give full play to its own advantages and devote itself to the specialization and serialization of pharmaceutical intermediates, so as to provide customers with high-quality, environmental protection and safety products. The company will also be honest, trustworthy, mutually beneficial and co-existence purposes, is willing to sincerely cooperate with customers at home and abroad, hand in hand.
Fast shipment by well-reputed shipping line;
Packaging with pallets according to buyers’ special request;
Cargoes together with container sales service available;
Providing best service after shipment by e-mail;
Providing photos of cargoes before and after loading into container;
If you want to find the best price of product, please contact Benoy Chemical.Emial:sales@benoychem.com
 

Details:

PENTOSTATIN Basic information
Product Name: PENTOSTATIN
Synonyms: CL-67310465:NSC-218321;(8R)-3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol;Pentostatin(Deoxycoformycin);Pentostatin, >=99%;ci-825;cl67310465;co-vidarabine;dcf
CAS: 53910-25-1
MF: C11H16N4O4
MW: 268.27
PENTOSTATIN Chemical Properties
Melting point  154-157 C
alpha  D25 +76.4° (c = 1 in water); D23 +73.0° (c = 1, pH 7 buffer)
Boiling point  411.43°C (rough estimate)
density  1.2576 (rough estimate)
refractive index  1.6081 (estimate)
storage temp.  Store at +4°C
solubility  H2O: soluble10mg/mL, clear
form  White solid
pka 5.2(at 25℃)
color  white to beige
optical activity [α]/D +70 to +80°, c = 1 in H2O
PENTOSTATIN Usage And Synthesis
Description Pentostatin, an adenosine deaminase inhibitor, is an orphan drug introduced for the treatment of hairy cell leukemia. The agent is considered a significant advance over alpha-interferon, the only other drug available for this indication. The majority of patients treated with pentostatin have been reported to remain in remission for at least four years. It is also under investigation for the treatment of other kinds of leukemia and in transplant rejection.
Chemical Properties White Solid
Originator Warner-Lambert (Parke-Davis) (U.S.A.)
Uses Pentostatin is a potent antitumour antibiotic isolated from a Streptomyces species. Pentostatin is a potent inhibitor of adenine deaminase and has been used therapeutically as an antitumour agent.
Uses Pentostatin is a potent antitumor antibiotic isolated from a Streptomyces species. Pentostatin is a potent inhibitor of adenine deaminase and has been used therapeutically as an antitumor agent.
Uses An adenosine deaminase inhibitor used as an anti-cancer therapeutic drug. Shown to be effective in the treatment of hairy cell leukemia as well as having use in the treatment of other types of cancer such as chronic lymphocytic leukemia.

 

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