DM4

Min.Order / FOB Price:Get Latest Price

0 Metric Ton	Negotiable

0 Metric Ton

Negotiable

Min.Order :0 Metric Ton
Purity: 98%
Payment Terms : T/T

Keywords

796073-69-3 Maytansinoid DM4 98%+, DM1

Quick Details

Appearance:White to off-white powder
Application:Cytotoxin
PackAge:As per request
ProductionCapacity:|Metric Ton|Day
Storage:Store in a tight container at -20℃
Transportation:Shipping at room temperature if less than 2 weeks.

Superiority:

Product in stock

Details:

DM4 is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody drug conjugate. It is a structural analogue of maytansine, is a new thiol-containing and potent maytansinoid. DM4 is a cytotoxic maytansinoid drug. It is synthesized in order to link maytansinoids to antibodies via disulfide bonds. Maytansinoids inhibit tubulin polymerization and microtubule assembly and enhance microtubule destabilization, so there is potent suppression of microtubule dynamics resulting in a mitotic block and subsequent apoptotic cell death.

View All