High purity CAS NO.314728-85-3 Piperazine

Details:

 

sunifiram is a research ampakine that is becoming very popular amongst researchers. sunifiram (dm-235) is a piperazine derived ampakine drug which acts as a positive allosteric

modulator of ampa receptors, and has nootropic effects in animal studies with significantly

higher potency thanpiracetam. a number of related compounds are known, the best known

being unifiram (dm-232)

this enhancement by sunifiram is associated with an increase inphosphorylation of ampar through activation of protein kinase ii(camkii) and an increase in phosphorylation of nmdar through activation of protein kinase c α (pkcα). more specifically, sunifiram stimulates the glycinebinding site of nmdar with concomitant pkcαactivation through src kinase. enhancement of pkcα activity triggers to potentiate hippocampal ltp through camkii activation. sunifiram improves cognitive deficits via cam kinase ii andprotein kinase c activation.

 

 

enhance mental intelligence; boost memory and leaning capabilities; improve brain power to solve problems and protect it from any chemical or physical injury; enhance motivation level;enhance the control of cortical/subcortical brain mechanism; improve sensory perception.

 

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