N-Me-L-Ala-maytansi...

N-Me-L-Ala-maytansinol

N-Me-L-Ala-maytansinol

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1 Gram

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  • Min.Order :1 Gram
  • Purity: ≥ 98%
  • Payment Terms : L/C

Keywords

77668-69-0 cas 77668-69-0 ADCs Cytotoxin

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BOC Sciences is a US-based provider of specially designed scaffolds and building blocks products and services for academic and governmental research institutes, pharmaceutical and biotechnology industry. We offer an extensive catalog of building blocks in a wide range of applications. #

Details:

DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability. DC0-NH2 is about 1000-fold more cytotoxic than commonly used anticancer drugs (ex. Doxorubicin). DC0-NH2 can bind to the minor groove of DNA, followed by alkylation of adenine residues by its propabenzindole (CBI) component. #

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