1,1'-Carbonyldiimidazole Carbonyldiimidazole 99% CDI
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1,1'-Carbonyldiimidazole Basic information
Product Name: 1,1'-Carbonyldiimidazole
Synonyms: CARBONYLDIIMIDAZOLE;CARBODIIMIDAZOLE;DI(1H-IMIDAZOL-1-YL)METHANONE;CDI;(DIIMIDAZOL-1-YL)KETONE
CAS: 530-62-1
MF: C7H6N4O
MW: 162.15
EINECS: 208-488-9
1,1'-Carbonyldiimidazole Chemical Properties
Melting point 117-122 °C(lit.)
Boiling point 288.83°C (rough estimate)
density 1.303 g/mL at 25 °C
refractive index n20/D1.434
storage temp. 2-8°C
solubility Soluble in dimethylformamide.
pka 2.90±0.10(Predicted)
form Crystalline Powder
color White to light cream
PH 7.7 (50g/l, H2O, 20℃)
PH Range 7.7 at 50 g/l
Water Solubility Insoluble in water
Sensitive Moisture Sensitive
1,1'-Carbonyldiimidazole Usage And Synthesis
Chemical Properties White crystalline powder
Uses Used in the synthesis of peptides. Contains up to 10% imidazole.
Uses peptide coupling reagent
Uses CDI is mainly employed to convert alcohols and amines into carbamates, esters, and ureas. It is also used in the synthesis of peptides and nucleoside triphosphates.
Uses 1,1'-Carbonyldiimidazole is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.
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